Gastroprotective Activity of Plant Chrozophora Plicata an Essential Herb in Unani Medicine Safi

Introduction An ulcer is a sore or lesion that forms in the lining of the stomach or duodenum where acid and pepsin are present. Ulcers in the stomach are called gastric or stomach ulcers. Those in the duodenum are called duodenal ulcers. In general, ulcers in the stomach and duodenum are referred to as peptic ulcers. Ulcers occur in the esophagus or in the first portion of the duodenum, the duodenal bulb. Ulcers can also be caused or worsened by drugs such as ethanol, aspirin, indomethacin, ibuprofen, and other NSAIDs. The phytochemical profile of this plant chrozophora plicata reveals the presence of sterols, alcohols, hydrocarbons. flavonoids, lignans, coumarins, tannins, phenanthrenes, quinones, phenolic acids, alkaloids, cyanogenic glucosides and glucosinolates. It is evident from the literature that flavonoids posseses antiulcer properties. Since there are no reports of isolation of active antiulcer principles of Chrozophora plicata, an herbal ingredient present in unani medicine safi, the present study is planned to exploit the antiulcer activity of herbal plant named Chrozophora plicata, Family: Euphorbiaceae by using ethanol induced ulcer model in rats.